J.C. White opened the store in 1852, but Charles C. Lowell purchased the store after many years serving its customers. In the early 20th-century, the store moved to Pearl Street, where it expanded its offerings, even selling gasoline for a time as the first automobiles hit the city. Although the shop moved to different retail spaces, C.C. Lowell continued to operate through the mid-1960s. When the business passed outside the family, the commitment to quality service remained intact. In October 2012, long time general manager of C.C. Lowell, Kristen Sciascia, purchased the store and eventually moved the store to it spacious new location on Pleasant St.